Orexin A 5mg

65.00€

Availability: 73 in stock

3 Products -5%

61.75 € /pc

6 Products -10%

58.50 € /pc

8 Products -15%

55.25 € /pc

Orexin A 5mg research-grade lyophilized peptide powder in a glass vial. This hypothalamic neuropeptide (also known as Hypocretin-1, Hcrt-1) is widely studied in experimental models of wakefulness, sleep–wake regulation, appetite control, energy balance and reward-related signaling.

Research Use Only: All products are intended exclusively for laboratory and scientific research. Not for human or veterinary use.

Purity

99%+ (HPLC, third-party tested)

Test Certificate

Available upon request (COA)

Form

Lyophilized peptide powder

Content

5mg Orexin A per vial

Packaging

Glass vial with sterile closure

Storage

Store lyophilized at 2–8 °C in a dry place, protected from light.

Molecular formula

C₁₅₂H₂₅₂N₄₄O₄₄S₂

Molecular weight

≈ 3,561.1 g·mol⁻¹

Sequence (human)

Pyr-Gly-Leu-Ser-Ser-Ala-Ser-Ser-Arg-Ser-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Ser-Gly-Ala-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Leu-NH₂

CAS number

205526-95-8

In laboratory workflows, lyophilized research peptides are typically handled with suitable sterile diluents such as bacteriostatic water (BAC). For a compatible research-only solvent, see Bacteriostatic water – 10 ml .

Research Overview

Orexin A 5mg is an endogenous hypothalamic neuropeptide derived from the prepro-orexin precursor and is one of the two orexin/hypocretin ligands alongside Orexin B. In experimental systems, Orexin A 5mg acts as a potent agonist at both Orexin Receptor 1 (OX1R) and Orexin Receptor 2 (OX2R), and is commonly used to probe sleep–wake circuitry, arousal states, feeding behavior, energy homeostasis and reward-related pathways in vitro and in vivo research models.

Primary Research Areas

Sleep–wake regulation and narcolepsy models: Used in laboratory studies investigating hypothalamic circuits that stabilize wakefulness and model narcolepsy-like phenotypes through dual OX1R and OX2R activation.
Arousal and vigilance: Applied in experimental systems to examine orexinergic modulation of cortical activation, neuronal excitability and behavioral arousal.
Appetite and energy balance: Studied in preclinical feeding and metabolic models to explore the influence of Orexin A 5mg on food intake, thermogenesis and metabolic signaling.
Reward and motivation circuitry: Employed to investigate orexinergic regulation of mesolimbic dopamine pathways and reward-driven behaviors.
Synaptic transmission and neuronal plasticity: Used in electrophysiological and imaging studies to characterize how Orexin A 5mg alters synaptic strength, firing patterns and network activity.

Find out what benefits peptides have

Discover how peptides can boost recovery, improve skin health, increase energy and support overall performance. Explained simply and clearly in this short video.

Why Limitless Biochem?

Limitless BioChem is a trusted supplier of research compounds. Our products meet strict quality standards and are compliant with EU requirements. We focus on the safe and reliable supply of peptides and pure compounds intended exclusively for research or collector purposes.

This product is not intended for human or veterinary use. It is for collection or research purposes only. It cannot be used as food, dietary supplement or medicine! The information provided in the text on this page is for educational purposes only and does not constitute medical or other advice.