SEMA (GLP-1) 10mg

74.90€

3 Products -5%

71.16 € /pc

6 Products -10%

67.41 € /pc

8 Products -15%

63.67 € /pc

SEMA (GLP-1) 10 mg research-grade lyophilized peptide powder supplied in a glass vial. SEMA (GLP-1) is a long-acting synthetic analog of human glucagon-like peptide-1 (GLP-1), engineered with sequence substitutions and acylation to enhance stability and duration of action, and studied as a potent GLP-1 receptor agonist in experimental metabolic research models.

Research Use Only: All products are intended exclusively for laboratory and scientific research. Not for human or veterinary use.

Purity

High-purity research grade

Test Certificate

View Certificate of Analysis

Form

Lyophilized peptide powder

Content

10 mg SEMA (GLP-1) per vial

Packaging

Glass vial with sterile closure

Storage

Store lyophilized at 2–8 °C (desiccated, protect from light)

Molecular formula

C₁₈₇H₂₉₁N₄₅O₅₉

Molecular weight

~4113.6 g·mol⁻¹

Sequence / structure

H-His-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-{diacid-C18-γGlu-(AEEA)2}-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH

CAS number

910463-68-2

In laboratory workflows, lyophilized research peptides are typically handled with suitable sterile diluents such as bacteriostatic water (BAC). For a compatible research-only solvent, see Bacteriostatic water – 10 ml .

Research Overview

SEMA (GLP-1) is a long-acting GLP-1 receptor agonist based on the human incretin hormone GLP-1 and modified with amino acid substitutions and fatty-acid acylation to increase resistance to enzymatic degradation. In experimental in vitro and in vivo models it is used to investigate GLP-1 receptor signaling and its impact on glucose homeostasis, insulin and glucagon dynamics, appetite-related pathways and gastrointestinal motility under controlled laboratory conditions.

Primary Research Areas

GLP-1 receptor agonism: used in models evaluating GLP-1 receptor activation, downstream cAMP signaling and effects on pancreatic islet function and peripheral tissues.
Glucose-dependent insulin secretion: applied in research on glucose-stimulated insulin release, β-cell function and glycemic excursions in normoglycemic and diabetogenic setups.
Glucagon suppression and hepatic output: investigated in preclinical systems studying how GLP-1 signaling modulates α-cell glucagon secretion and hepatic glucose production.
Appetite regulation and satiety pathways: used in models exploring central and peripheral mechanisms of appetite, food intake behavior and satiety-related neuroendocrine circuits.
Metabolic and cardiometabolic endpoints: included in broader metabolic research on body weight regulation, adiposity, lipid profiles and cardiovascular risk markers in response to GLP-1 pathway modulation.

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Why Limitless Biochem?

Limitless BioChem is a trusted supplier of research compounds. Our products meet strict quality standards and are compliant with EU requirements. We focus on the safe and reliable supply of peptides and pure compounds intended exclusively for research or collector purposes.

This product is not intended for human or veterinary use. It is for collection or research purposes only. It cannot be used as food, dietary supplement or medicine! The information provided in the text on this page is for educational purposes only and does not constitute medical or other advice.