TIRZ (GLP-2) 10mg

96.30€

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TIRZ (GLP-2) 10 mg
research-grade
lyophilized peptide powder
supplied in a glass vial. This compound, also referred to as
LY3298176,
is an incretin peptide analog studied as a dual agonist at the GIP (glucose-dependent insulinotropic polypeptide) and GLP-1
(glucagon-like peptide-1) receptors in experimental metabolic research models.

Research Use Only:
All products are intended exclusively for laboratory and scientific research. Not for human or veterinary use.

Purity

High-purity research grade

Test Certificate

View Certificate of Analysis

Form

Lyophilized peptide powder

Content

10 mg TIRZ (GLP-2) per vial

Packaging

Glass vial with sterile closure

Storage

Store lyophilized at 2–8 °C (desiccated, protect from light)

Molecular formula

C₂₂₅H₃₄₈N₄₈O₆₈

Molecular weight

~4813.5 g·mol⁻¹

Sequence / structure

Tyr-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{Aib}-Leu-Asp-Lys-{diacid-C20-γGlu-(AEEA)2}-Ala-Ala-Gln-{Aib}-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH₂

CAS number

2023788-19-2

In laboratory workflows, lyophilized research peptides are typically handled with suitable sterile diluents such as bacteriostatic water (BAC).

For a compatible research-only solvent, see

Bacteriostatic water – 10 ml
.

Research Overview

TIRZ (GLP-2), also known as LY3298176, is a synthetic incretin peptide analog investigated as a dual agonist at the GIP and GLP-1 receptors.
In experimental in vitro and in vivo models it is used to explore how concurrent activation of these incretin pathways affects glucose handling,
insulin secretion, glucagon regulation, gastric emptying, appetite-related signaling and broader metabolic endpoints.

Primary Research Areas

Dual GIP and GLP-1 receptor agonism:
used in studies assessing combined activation of GIP and GLP-1 receptors and its impact on incretin signaling cascades in metabolic research models.
Glucose control and insulin sensitivity:
applied in experimental systems examining insulin secretion, glucagon suppression, glycemic excursions and insulin sensitivity under controlled
laboratory conditions.
Body weight and adiposity models:
investigated in preclinical models of body weight regulation, adipose tissue remodeling and energy balance in the context of incretin pathway modulation.
Appetite regulation and gastric emptying:
used to study satiety signaling, food intake behavior and gastric emptying rate in animal and cellular models related to appetite control.
Cardiometabolic health markers:
included in broader cardiometabolic research evaluating lipid parameters, inflammatory markers and vascular endpoints associated with incretin-based modulation.

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Why Limitless Biochem?

Limitless BioChem is a trusted supplier of research compounds. Our products meet strict quality standards and are compliant with EU requirements. We focus on the safe and reliable supply of peptides and pure compounds intended exclusively for research or collector purposes.

This product is not intended for human or veterinary use. It is for collection or research purposes only. It cannot be used as food, dietary supplement or medicine! The information provided in the text on this page is for educational purposes only and does not constitute medical or other advice.