KY-19382 5 mg/ml – solution 30 ml

169.00€

3 Products -5%

160.55 € /pc

6 Products -10%

152.10 € /pc

8 Products -15%

143.65 € /pc

KY-19382 5 mg/ml – solution 30 ml research-grade small-molecule solution supplied in a 30 ml glass bottle. KY-19382 is a synthetic indirubin-derived compound studied as a dual modulator of the Wnt/β-catenin signaling pathway, described in the literature as inhibiting GSK3β activity and interfering with the CXXC5–DVL interaction in experimental models investigating bone growth, cartilage biology, metabolic regulation and hair-follicle regeneration.

Research Use Only: All products are intended exclusively for laboratory and scientific research. Not for human or veterinary use.

Purity

High-purity research grade

Form

Clear research solution

Content

5 mg KY-19382 per 1 ml; 30 ml per bottle (total 150 mg KY-19382 per bottle)

Packaging

30 ml glass bottle with sterile closure

Storage

Store at 2–8 °C; protect from light.

Molecular formula

C₁₇H₁₁Cl₂N₃O₂

Molecular weight

360.19 g·mol⁻¹

IUPAC name

2H-indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro

CAS number

2226664-93-1

Research Overview

KY-19382 is a synthetic indirubin-derived small molecule used as a tool compound in studies of Wnt/β-catenin signaling. In preclinical work it has been characterized as a dual modulator that can inhibit GSK3β activity and interfere with the CXXC5–DVL interaction, leading to enhanced Wnt/β-catenin pathway activity in selected experimental systems. Laboratory research employs KY-19382 in cell and tissue models focused on bone and cartilage growth, hair-follicle biology, metabolic regulation and other Wnt-dependent processes under strictly controlled conditions.

Primary Research Areas

Wnt/β-catenin pathway modulation: used in in vitro and in vivo models to study how dual modulation of GSK3β activity and the CXXC5–DVL interface impacts β-catenin stabilization, nuclear translocation and transcriptional activation of Wnt target genes in development and regeneration research.
Bone growth and cartilage / chondrogenesis models: applied in studies of growth plate biology, chondrocyte proliferation and differentiation, and longitudinal bone growth, where altered Wnt/β-catenin signaling is examined in the context of skeletal development and age-related growth plate senescence.
Hair follicle and skin regeneration research: incorporated into experimental systems investigating hair-follicle cycling, hair shaft elongation and dermal regeneration, including models where Wnt/β-catenin signaling activators are evaluated under metabolic or hyperglycemic stress conditions.
Metabolic and endocrine signaling models: used as a probe compound in studies exploring how modulation of Wnt/β-catenin signaling intersects with pathways relevant to metabolic homeostasis, glucose handling and adipocyte or hepatocyte biology in preclinical settings.
Wnt-dependent disease and oncology research: evaluated in cell and tissue models of Wnt-related pathologies, including fibrosis and selected tumor systems, where dysregulated Wnt/β-catenin activity is a key mechanistic focus of laboratory investigation.

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Limitless BioChem is a trusted supplier of research compounds. Our products meet strict quality standards and are compliant with EU requirements. We focus on the safe and reliable supply of peptides and pure compounds intended exclusively for research or collector purposes.

This product is not intended for human or veterinary use. It is for collection or research purposes only. It cannot be used as food, dietary supplement or medicine! The information provided in the text on this page is for educational purposes only and does not constitute medical or other advice.