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CJC-1295 NO DAC 5mg
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CJC-1295 NO DAC 5 mg research-grade lyophilized peptide powder supplied in a glass vial. CJC-1295 NO DAC, also known as Modified GRF (1-29) or Mod GRF 1-29, is a synthetic peptide analog of Growth Hormone-Releasing Hormone (GHRH) studied in experimental models of pituitary growth hormone release, GHRH receptor agonism and pulsatile GH secretion.
Research Overview
CJC-1295 NO DAC (Modified GRF 1-29) is a synthetic analog of Growth Hormone-Releasing Hormone composed of the first 29 amino acids of native GHRH with selected substitutions to enhance stability and receptor affinity. In experimental in vitro and in vivo models it is used to investigate pituitary growth hormone release, GHRH receptor activation and short-lived, pulsatile GH secretion patterns under controlled conditions.
Primary Research Areas
- GHRH receptor agonism: used to study selective activation of the Growth Hormone-Releasing Hormone receptor and downstream cAMP/PKA signaling in pituitary and related cellular models.
- Growth hormone (GH) release: applied in experimental systems evaluating GH pulse amplitude and frequency, pituitary responsiveness and feedback regulation of the somatotropic axis.
- Pulsatile secretion patterns: investigated for its short half-life profile and use in models designed to mimic physiological, pulsatile GH release rather than continuous exposure paradigms.
- Pituitary function assessment: included in research protocols probing pituitary reserve, GH–IGF-1 axis integrity and interactions with other hypothalamic–pituitary hormones in animals and ex vivo tissues.
- Combination with GHRPs/GHSs: used in combination studies with growth hormone secretagogues (GHRPs/GHSs) to explore potential synergistic or additive effects on GH release and downstream signaling endpoints in laboratory models.
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- Warning
This product is not intended for human or veterinary use. It is for collection or research purposes only. It cannot be used as food, dietary supplement or medicine! The information provided in the text on this page is for educational purposes only and does not constitute medical or other advice.