KW-6356 (Sipagladenant) 1mg – 60 tablets

96.00€

Availability: 2 in stock

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91.20 € /pc

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81.60 € /pc

KW-6356 (Sipagladenant) 1 mg – 60 tablets research-grade tablets in a sealed bottle. Sipagladenant (KW-6356) is a selective adenosine A_2A receptor antagonist/inverse agonist investigated in laboratory models of basal ganglia circuitry, cAMP signaling, dopaminergic modulation and neuroplasticity.

Research Use Only: All products are intended exclusively for laboratory and scientific research. Not for human or veterinary use.

Purity

High-purity research grade

Form

Tablets

Content

1 mg Sipagladenant per tablet

Total tablets

60 tablets (total 60 mg per bottle)

Packaging

Sealed tablet bottle

Storage

Store in a cool, dry place at room temperature; protect from light.

Molecular formula

C₂₀H₁₉N₃O₄S

Molecular weight

≈ 397.45 g·mol⁻¹

IUPAC name

N-(4-(furan-2-yl)-5-(tetrahydro-2H-pyran-4-carbonyl)thiazol-2-yl)-6-methylnicotinamide

CAS number

858979-50-7

Research Overview

KW-6356 is applied in experimental systems to interrogate A_2A-receptor control of basal ganglia networks and cAMP/PKA signaling. Research frequently examines dopaminergic modulation, synaptogenesis markers, transcriptional programs linked to plasticity, and resilience under stress paradigms in vitro and in vivo.

Primary Research Areas

A_2A adenosine receptor signaling: Antagonism/inverse agonism and cAMP pathway readouts.
Basal ganglia circuitry: Striatal pathway modulation in neuronal models.
Dopaminergic modulation: Interactions with D₂-linked signaling and synaptic endpoints.
Neuroplasticity & synaptogenesis: Spine density and synaptic protein markers under controlled conditions.

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Why Limitless Biochem?

Limitless BioChem is a trusted supplier of research compounds. Our products meet strict quality standards and are compliant with EU requirements. We focus on the safe and reliable supply of peptides and pure compounds intended exclusively for research or collector purposes.

This product is not intended for human or veterinary use. It is for collection or research purposes only. It cannot be used as food, dietary supplement or medicine! The information provided in the text on this page is for educational purposes only and does not constitute medical or other advice.