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CJC-1295 with DAC 5mg
89.00€
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CJC-1295 with DAC 5 mg research-grade lyophilized peptide powder supplied in a glass vial. CJC-1295 with DAC is a synthetic analog of Growth Hormone-Releasing Hormone (GHRH), incorporating Drug Affinity Complex (DAC) technology to enable covalent binding to serum albumin and extend circulating half-life in experimental models of GH/IGF-1 axis regulation.
Research Overview
CJC-1295 with DAC is a long-acting GHRH analog based on the first 29 amino acids of human Growth Hormone-Releasing Hormone (Modified GRF 1-29), further modified with a maleimidopropionyl Drug Affinity Complex (DAC) linked via lysine. In experimental in vitro and in vivo systems, this design enables covalent binding to circulating albumin, markedly prolonging half-life and allowing sustained stimulation of GHRH receptors, growth hormone (GH) secretion and downstream insulin-like growth factor 1 (IGF-1) signaling under controlled laboratory conditions.
Primary Research Areas
- Sustained GH release: used in models examining prolonged pituitary growth hormone output following extended GHRH receptor stimulation and albumin binding–mediated half-life extension.
- IGF-1 axis modulation: applied in research exploring long-term elevations in circulating IGF-1, somatotropic axis activity and associated metabolic endpoints in preclinical settings.
- Extended GHRH receptor agonism: used to study receptor occupancy, downstream cAMP/PKA signaling and desensitization or adaptation phenomena during chronic GHRH analog exposure.
- Metabolism and body composition models: incorporated into experimental designs evaluating how prolonged GH/IGF-1 elevation influences body composition, tissue remodeling and energy metabolism markers in animals and other laboratory systems.
- Pharmacokinetics of long-acting peptides: used as a model compound in studies on albumin-binding peptide drugs, half-life extension strategies and modified-release endocrine analogs.
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- Warning
This product is not intended for human or veterinary use. It is for collection or research purposes only. It cannot be used as food, dietary supplement or medicine! The information provided in the text on this page is for educational purposes only and does not constitute medical or other advice.