O-304 (ATX) 100mg – 30 capsules

139.00€

Availability: 88 in stock

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132.05 € /pc

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118.15 € /pc

O-304 (ATX) 100 mg – 30 capsules research-grade Autotaxin (ATX) inhibitor in capsule form supplied in a sealed bottle. This synthetic small molecule is studied as a potent and selective inhibitor of Autotaxin (ENPP2), the key enzyme responsible for extracellular lysophosphatidic acid (LPA) production in experimental models.

Research Use Only: All products are intended exclusively for laboratory and scientific research. Not for human or veterinary use.

Purity

High-purity research grade

Form

Research capsules

Content

100 mg O-304 per capsule

Total count

30 capsules (total 3,000 mg per bottle)

Packaging

Sealed bottle

Storage

Store at room temperature, protect from light, keep desiccated

Molecular formula

C₂₅H₂₃F₃N₂O₅S

Molecular weight

~536.5 g·mol⁻¹

IUPAC name

3-[[4-[5-[3,5-dichloro-4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-3-yl]phenyl]methyl]-5-(hydroxymethyl)-2-oxazolidinone

CAS number

936087-73-7

Research Overview

O-304 is a synthetic small molecule inhibitor of Autotaxin (ATX), also known as ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2). ATX catalyzes the extracellular production of lysophosphatidic acid (LPA), a bioactive lipid mediator involved in cell proliferation, migration, survival, inflammation and fibrosis. In experimental in vitro and in vivo models, O-304 is used to investigate how selective ATX inhibition and subsequent LPA reduction affect pathological remodeling processes and disease-relevant signaling pathways.

Primary Research Areas

Autotaxin (ATX/ENPP2) enzyme inhibition: used to study potent and selective inhibition of Autotaxin activity and its downstream impact on LPA signaling in biochemical and cell-based assays.
Lysophosphatidic acid (LPA) pathway modulation: applied in research examining how reduced LPA production influences GPCR-mediated signaling, cell motility, survival and tissue remodeling in experimental systems.
Fibrosis models: investigated in preclinical models of fibrotic disease, including liver and lung fibrosis, where ATX–LPA signaling is implicated in excessive extracellular matrix deposition and chronic tissue injury.
Inflammatory signaling and immune modulation: used in studies focusing on inflammatory pathways, immune-cell trafficking and cytokine networks influenced by LPA and ATX activity in vitro and in vivo.
Cancer proliferation and migration: explored in oncology-oriented models where aberrant ATX–LPA signaling contributes to tumor cell proliferation, survival, invasion and metastasis in controlled laboratory settings.

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Limitless BioChem is a trusted supplier of research compounds. Our products meet strict quality standards and are compliant with EU requirements. We focus on the safe and reliable supply of peptides and pure compounds intended exclusively for research or collector purposes.

This product is not intended for human or veterinary use. It is for collection or research purposes only. It cannot be used as food, dietary supplement or medicine! The information provided in the text on this page is for educational purposes only and does not constitute medical or other advice.