Peptide 5 (Connexin 43) 5mg

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Peptide 5 (Connexin 43) 5 mg
research-grade
lyophilized peptide powder
supplied in a glass vial. Peptide 5, also known as
αCT1 (alpha Connexin carboxyl-terminal 1),
is a synthetic nonapeptide corresponding to the C-terminal sequence of Connexin 43 (Cx43) that is studied in experimental models of gap
junction modulation, tissue repair and cell–cell communication.

Research Use Only:
All products are intended exclusively for laboratory and scientific research. Not for human or veterinary use.

Purity

99%+ (HPLC, third-party tested)

Form

Lyophilized peptide powder

Content

5 mg Peptide 5 (αCT1) per vial

Packaging

Glass vial with sterile closure

Storage

Store lyophilized at 2–8 °C (desiccated, protect from light)

Molecular formula

C₄₇H₇₈N₁₄O₁₆

Molecular weight

~1099.2 g·mol⁻¹

Sequence

Arg-Pro-Arg-Pro-Asp-Asp-Leu-Glu-Ile

CAS number

1373327-02-1

In laboratory workflows, lyophilized research peptides are typically handled with suitable sterile diluents such as bacteriostatic water (BAC).

For a compatible research-only solvent, see

Bacteriostatic water – 10 ml
.

Research Overview

Peptide 5 (αCT1) is a synthetic nonapeptide corresponding to the final nine amino acids of the Connexin 43 (Cx43) C-terminus. In experimental
in vitro and in vivo models it is used to investigate how targeted modulation of Cx43–ZO-1 interactions and gap junction organization can
influence intercellular communication, barrier integrity and tissue repair processes in diverse organs and tissues.

Primary Research Areas

Gap junction modulation:
used in studies examining how modulation of Connexin 43-containing gap junctions alters intercellular coupling, electrical conductance and
signaling in cardiac, epithelial and other tissue models.
Connexin 43 / ZO-1 interaction:
applied to probe interactions between the Cx43 C-terminus and scaffolding proteins such as Zonula occludens-1 (ZO-1), and how these complexes
regulate junctional organization and barrier properties.
Wound healing and tissue repair models:
investigated in skin, corneal and other injury models where altered gap junction communication and Cx43 distribution are linked to tissue
repair dynamics and structural recovery endpoints.
Cardiac protection and anti-arrhythmic research:
used in preclinical cardiac models exploring whether targeted manipulation of Cx43-containing gap junctions can influence conduction
heterogeneity, arrhythmia susceptibility and myocardial injury responses under controlled conditions.
Cell–cell communication in diverse tissues:
included in broader research on how connexin-based junctions coordinate cell behavior, growth and differentiation across epithelial,
endothelial and other cellular networks.

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Why Limitless Biochem?

Limitless BioChem is a trusted supplier of research compounds. Our products meet strict quality standards and are compliant with EU requirements. We focus on the safe and reliable supply of peptides and pure compounds intended exclusively for research or collector purposes.

This product is not intended for human or veterinary use. It is for collection or research purposes only. It cannot be used as food, dietary supplement or medicine! The information provided in the text on this page is for educational purposes only and does not constitute medical or other advice.